With the expansion of new technologies in governance, artificial intelligence has become a key tool in decision-making and public policy. Although the application of this technology within the country’s policymaking system remains in its early or limited stages, the shift toward intelligent decision-support systems has made it increasingly necessary to identify the human requirements of this transformation. Nevertheless, the human dimensions that shape policymakers’ interactions with intelligent decision-support systems warrant further investigation. This study aims to identify and elucidate the human factors influencing policymakers’ participation in AI-based decision-making processes. This qualitative study employs thematic analysis and collected data through semi-structured interviews with 20 experts in public policy and digital transformation. The findings identified six overarching themes: cognitive competence; psycho-behavioral characteristics and communication capabilities; attitudes toward technology; professional experience; and institutional and contextual conditions. These themes comprised 14 main themes and 39 basic themes, reflecting the diverse and complex dimensions of human factors in intelligent decision-making. The results emphasize that the effective use of intelligent systems requires strengthening human capacities alongside the development of technological infrastructures.